I just upgraded to 2.4.5 and things look good except for the backend which is sometimes displaying an incomplete site-tree. Some of the base nodes are there but any pages in the site tree with children (the important ones!) don't show up in the CMS panel. The front end is rendering fine.
This is really weird and does not seem to have to do with the cache on the server side as flushing as well as deleting the cache files does not seem to help. It seems like the browser is getting some kind of corrupted or incomplete AJAX bits and caching it. The one thing that seemed to work was switching tabs in the CMS and then doing a shift-refresh to clear the browser cache. This happens on Firefox, Chrome and Safari.
Any help or suggestions would be great as my users are a little annoyed and confused.